NAD+
NicotinamideАdenineDinucleotide or NAD+ is a vitamin B3 coenzyme that is vital to every cell in the human body.
This miracle molecule is essential for energy synthesis, cellular regeneration, preventing aging, and repairing DNA damage.
NAD+ is considered a key factor for healthy aging and longevity.
NAD+
- parkinson's disease, Alzheimer's disease
- hypertension
- diabetes mellitus
- cardiovascular diseases
- liver diseases
- immune diseases
- concentration disorders, memory problems
- alcohol and drug addiction
- depression and anxiety
- chronic stress
- sleep problems
- chronic fatigue
- anti-aging programs
- overweight and obesity
- loss of energy and overall tone
How it works
NAD+ is crucial to life because it is directly involved in the functioning of the mitochondria and the production of ATP energy (the mitochondria are our cell's mini power plant, generating the energy through which the body lives).
In cells, NAD exists in two states NAD+ and NADH - oxidized and reduced forms. Both of these compounds are part of the same energy production process, moving from one to the other through various reactions. The balance of NAD+ and NADH is important for life.
Unfortunately, NAD+ levels decrease with age, and scientists believe that this decrease may be directly related to aging.
NAD+ levels decrease in everyone as they age, regardless of your personal health, diet or fitness. NAD+ decreases by 50% at age 40 and up to 80% by age 60.
NAD+ anti-aging molecule
Recent scientific research suggests that NAD+ is involved not only in the production of energy necessary for human life, but also plays an important role in almost all currently known mechanisms of human aging.
For example, NAD+ is an important direct cofactor of key enzymes responsible for longevity, called sirtuins. Sirtuins, SIRT1-7, are closely linked to longevity by controlling gene expression and require NAD+ for their activity. By activating sirtuins, we can gain control over "aging.
SIRTs "turn off" genes that contribute to aging, such as those involved in inflammation, fat synthesis and storage, and blood sugar regulation. SIRTs restore and lengthen telomeres (protective caps at the ends of DNA), participate in the regulation of oxidative stress, etc.
In simple words sirtuins prolong life by reducing the incidence of age-related diseases (diabetes, general inflammation, fat accumulation, immunity regulation), and NAD+ activates sirtuins.
There are studies that confirm that NAD+ plays a role in other aging mechanisms: it is involved in DNA damage repair, epigenetic signal transduction, mitochondrial synthesis, maintenance of chromosome integrity, and more.
Role of NAD+ in prevention of chronic neurodegenerative diseases
There is a direct link between energy production and chronic disease. Low NAD+ leads to low levels of ATP. Low ATP levels quickly deplete your cell's energy stores, which accelerates cell death.
How this manifests itself in your body depends on which cells are affected:
- If nerve cells are affected, the lack of energy can manifest as depression, anxiety, fatigue, and lack of concentration
- long-term effects on nerve cells can lead to symptoms such as tremors, cramps, tingling, numbness, and blurred vision. There is speculation that severe energy disturbances in the cell may be the cause of neurodegenerative diseases such as Parkinson's disease and multiple sclerosis
- if heart cells are affected, it can lead to cardiovascular diseases
- if lung cells are affected, lung disorders can manifest
In general, we know that when the cells in your organs and tissues lack energy, disease occurs.
The role of NAD+ in exercise, sport, and endurance
ATP levels are depleted in muscles during exercise is an understandable process. Until recently, however, we did not know how NAD+ was involved in this process.
Intense exercise decreases NAD+, and the addition of substances that stimulate NAD+ formation increases endurance, shortens the recovery period, and increases performance.
The role of NAD+ in addiction
NAD+ has been used since 1967 in the treatment of drug and alcohol addiction. Although the mechanisms of the therapy are not fully understood, the results are impressive: patients report a reduction in withdrawal symptoms and a general recovery from addiction within 7-14 days of therapy.
Perhaps one of the mechanisms of addiction formation is the role of NAD+ in alcohol metabolism.
EXPERT OPINION
FOR WHOM
Benefits of NAD+
- increases your body's ability to recover from stress and tension
- strengthens your ability to work during physical exercise, increasing your endurance
- helps counteract the effects of unhealthy diet and lack of exercise
- inhibits DNA damage and protects telomeres
- boosts energy
- enhances cognitive function (memory, thinking, comprehension, learning)
- maintains the health of the cardiovascular system, liver, and other internal organs
- blunts depressive episodes
- skin quality
PRICE
Depends on the NAD+ therapy program chosen: IV NAD drips, NAD-boosters or NAD+ supplements
At the consultation with a doctor from Total Concept Aesthetics you will learn which NAD+ therapy program is good for you, its special features and its cost.
Make an appointment and get answers on how to stay healthy, attractive and full of energy, regardless of your age.
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